Gill and colleagues used magnetic resonance imaging (MRI) of the foot to determine a positive relationship between the size of the lateral plantar process and the peroneal tubercle in the human calcaneus. This study refuted observations made over the past 80 years and clarified evolutionary and biomechanical implications within the human lineage and fossil record.
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In a study in the journal Radiology, Bredella and colleagues used 1H-MRS to quantify bone marrow fat content, intramyocellular lipids and intrahepatic lipids, concluding that ectopic and serum lipids are positively associated with bone marrow fat in obese men and women.
Because bone marrow fat is known to be inversely related to BMD, these results support the notion that ectopic and serum lipid levels are influenced by the same additional factors as bone marrow or may exert negative effects on bone.